Banks in Missouri

16 FDIC-insured banks headquartered in Missouri, ranked by total assets.

Missouri is home to 16 FDIC-insured banks holding a combined $214.45B in total assets and approximately $180.44B in deposits (Source: FDIC BankFind). These figures represent banks headquartered in Missouri and may not include all branches of out-of-state banks operating in the state.

UMB Bank is the largest bank headquartered in Missouri with $72.78B in total assets, indicating moderate market concentration among the largest institutions (Source: FDIC BankFind). The mix of national banks, regional institutions, and community banks in Missouri provides consumers with a range of options based on their banking preferences.

Total Banks

Combined Assets

$214.45B

Avg ROA

1.32%

Largest banks in Missouri

UMB Bank

UMB Bank is the largest bank headquartered in Missouri with $72.78B in total assets and 209 branches (Source: FDIC BankFind).

Commerce Bank

Commerce Bank is a major bank headquartered in Missouri with $32.72B in total assets and 144 branches (Source: FDIC BankFind).

The Central Trust Bank

The Central Trust Bank is a major bank headquartered in Missouri with $20.80B in total assets and 172 branches (Source: FDIC BankFind).

Stifel Bank and Trust

Stifel Bank and Trust is a major bank headquartered in Missouri with $19.41B in total assets and 2 branches (Source: FDIC BankFind).

Enterprise Bank & Trust

Enterprise Bank & Trust is a major bank headquartered in Missouri with $17.27B in total assets and 58 branches (Source: FDIC BankFind).

Banks headquartered in Missouri

#	Bank	Total Assets	Deposits	ROA	Branches
1	UMB Bank, National AssociationKansas City	$72.78B	$61.06B	1.01%	209
2	Commerce BankKansas City	$32.72B	$25.94B	1.74%	144
3	The Central Trust BankJefferson City	$20.80B	$16.77B	1.82%	172
4	Stifel Bank and TrustSaint Louis	$19.41B	$17.86B	1.82%	2
5	Enterprise Bank & TrustClayton	$17.27B	$14.76B	1.29%	58
6	Stifel BankSaint Louis	$11.74B	$10.81B	1.49%	1
7	First BankSt. Louis	$6.65B	$5.97B	0.51%	76
8	Great Southern BankReeds Spring	$5.60B	$4.54B	1.31%	112
9	Southern BankPoplar Bluff	$5.04B	$4.32B	1.36%	70
10	First State Community BankFarmington	$4.47B	$3.75B	1.74%	53
11	Academy Bank, National AssociationKansas City	$3.32B	$2.78B	0.80%	80
12	Oakstar BankSpringfield	$3.04B	$2.68B	1.18%	28
13	The Bank of MissouriPerryville	$3.04B	$2.50B	1.65%	29
14	Midwest BankCentreLemay	$2.98B	$2.46B	1.10%	18
15	North American Savings Bank, F.S.B.Grandview	$2.97B	$1.90B	0.99%	10
16	Lead BankKansas City	$2.62B	$2.34B	1.34%	2

Source: FDIC BankFind, most recent quarterly data. Only includes banks headquartered in Missouri. Data last updated: April 2, 2026.

Credit unions in Missouri

2 credit unions headquartered in Missouri, ranked by total assets. Credit unions are member-owned cooperatives insured by the NCUA.

#	Credit Union	Total Assets	Members	ROA	Branches
1	FIRST COMMUNITYChesterfield	$4.84B	408,317	0.80%	N/A
2	TOGETHERSaint Louis	$2.66B	145,653	0.56%	N/A

Source: NCUA Quarterly Call Report Data. Only includes credit unions headquartered in Missouri.

How to choose a bank in Missouri

When choosing a bank in Missouri, consider what matters most for your financial needs. Missouri has 16 FDIC-insured banks headquartered in the state, plus additional out-of-state banks with local branches. Each institution offers different strengths in terms of branch access, product variety, and community focus.

Consider whether branch access matters to you. If you prefer in-person banking, look for institutions with branches near your home or workplace. If you primarily use mobile and online banking, you may want to prioritize digital features and compare interest rates, as online-focused banks often offer higher savings APYs.

All banks listed on this page are FDIC-insured, meaning deposits are protected up to $250,000 per depositor, per insured bank, for each account ownership category (Source: FDIC). Beyond FDIC insurance, compare factors such as monthly maintenance fees, ATM networks, minimum balance requirements, and customer service availability. The CFPB recommends comparing at least three institutions before opening a new account.

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Data Sources

FDIC BankFind: Financial data including total assets, deposits, net income, ROA, and ROE for all FDIC-insured institutions. https://banks.data.fdic.gov/

CFPB Consumer Complaint Database: Consumer complaint data by institution, including complaint volumes, response rates, and top issue categories. https://www.consumerfinance.gov/data-research/consumer-complaints/

Federal Reserve Economic Data (FRED): Interest rate benchmarks including the Federal Funds Rate, Treasury yields, and national savings rate averages. https://fred.stlouisfed.org/

BankRanked is not a bank, credit union, or financial advisor. This content is for educational purposes only and does not constitute financial advice. All data is sourced from publicly available government databases (FDIC, NCUA, CFPB, FRED). Consult a licensed financial professional before making banking decisions.